Polymyxin B Sulfate (non-sterile)
MATERIAL SAFETY DATA SHEET
Polymyxin B sulfate
01 - Identification of the substance / Preparation and company
Identification of the manufacturer
976 13 Slovenska Lupca 566
Tel.: 00421/48/4368 111
Fax: 00421/48/418 7058
Identification of the product
1.1. Commercial product name: Polymyxin B sulfate
02 - COMPOSITION / Information on ingredients
2.1. Chemical characterization (substance):
03 - HAZARDS IDENTIFICATION
3.1. Critical hazards to man and environment:
Human health hazards:
May be harmful if swallowed.
May cause damage to the following organs: kidneys, gastrointestinal tract, muscle tissue
04 - FIRST-AID MEASURES
4.1. General information: -
4.2. After inhalation:
If inhales, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
4.3. After contact with the skin:
In case of contact, immediately flush skin with plenty of water. Remove contaminated clothing and shoes. Cold water may be used. Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medical attention.
4.4. After contact with the eyes:
Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Cold water may be used. Get medical attention.
4.5. After swallowing:
Do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight clothing such as a collar, tie, belt or waistband.
5 - FIRE-FIGHTING MEASURES
5.1. Suitable extinguishing media:
Small fire: Use dry chemical powder.
Large fire: Use water spray, fog or foam. Do not water jet.
5.2. Extinguishing media which must not be used for safety reasons:
5.3. Special exposure hazards arising from the substance or preparation itself, combustion products, resulting gases:
Hazardous combustion products: These products are nitrogen oxides (NO, NO2).
5.4. Special protective equipment for fire fighting:
Be sure to use approved/certified respirator or equivalent.
06 - ACCIDENTAL RELEASE MEASURES
6.1 Personal precautions:
Splash goggles. Full suit. Boots. Gloves. Suggested protective clothing might be sufficient, consult specialist before handling this product.
6.2. Environmental precautions:
Cover any spilled material in accordance with regulations to prevent dispersal by wind. Observe local bye-laws.
6.3. Methods for cleaning up:
Use appropriate tools to put the spilled solid a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to local and regional authority requirements. In cage of large spill and leak use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface an allow to evacuate through the sanitary system
07 - HANDLING AND STORAGE
Keep away from heat. Keep away from sources of ignition. Empty bags pose risk, evaporate the residue under a fume hood. Ground all equipment containing material. Do not ingest. Do not breath dust. Wear suitable protective clothing. If ingested, seek medical advices immediately and show the bag or the label.
Keep bag tightly closed. Keep bag in cool, well-ventilated area. Do not store above 20°C (68°F).
Packing materials: Use original bag.
08 - EXPOSURE CONTROLS/PERSONAL PROTECTION
8.1. Further information for system design and engineering measures:
Observe information in section 7. Use process enclosures, local ventilation, or other engineering controls to keep airborn levels below recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborn contaminants below the exposure limit.
8.2. Personal protection equipment
General protection and hygiene measures:
Do not eat, drink or smoke when handling. Avoid contact with eyes and skin. Do not breath dust.
When dust formation fine dust mask without protection rating.
Protective gloves recommended.
09 - PHYSICAL AND CHEMICAL PROPERTIES
solid - powder
white or almost white powder, hygroscopic
odourless or faint odour
9.2. Safety parameters
> 240 °C
Lower explosion point:
no data at hand
Upper explosion point:
no data at hand
approx. 250 kg/m3
Solubility in water:
easily soluble in cold water
9.3. Further information
This material is assumed to be combustible. As with all dry powder it is advisable to ground mechanical equipment in contact with dry material to dissipate the potential buildup of static electricity.
Risk of explosion of the product in presence of mechanical impact:
Risk of explosion of the product in presence of static discharge:
10 - STABILITY AND REACTIVITY
10.0. General information:
Reacts with strong oxidation agents.
10.1. Conditions to avoid:
10.2. Materials to avoid:
10.3. Hazardous decomposition products:
These products are nitrogen oxides (NO, NO2).
11 - TOXICOLOGICAL INFORMATION
11.0. General information:
11.1. Acute toxicity: LD 50:
Repeated or prolonged exposure is not known to aggravate medical condition.
Other toxic effect on humans:
Not available. Hazardous in case of ingestion. Exposure can cause nausea, headache and vomiting. Repeated or prolonged exposure to the substance can produce kidney damage. May cause convulsion.
12 - ECOLOGICAL INFORMATION
12.1. Information on elimination (persistence and degradability)
No data known.
12.2. Behaviour in environmental compartments
No harmful effects expected.
12.3. Ecotoxicological effects
No likelihood of damaging effect on water organisms.
Effects in sewage treatment plants (bacteria toxicity: respiration -/reproduction inhibition):
According to present experience, no adverse effects on water purification plants.
12.4. Further ecological information
Do not introduce into waters and into soil.
13 - DISPOSAL CONSIDERATIONS
Recommendation: Waste must be disposed of in accordance with federal, state and local environmental control regulations.
13.2. Contaminated packaging
Recommended cleaning agent: Water.
14 - TRANSPORT INFORMATION
International transport regulations
Land – Road/Railway
Not controlled ADR (Europe).
Not controlled under IMDG.
IATA – DGR Class:
Not controlled under IATA.
Special provisions for transport:
15. REGULATORY INFORMATION